Visited last week Feb-2012.
Day 1 (Arrival mid-day)
We had taken a morning Ryan Air flight from Paris Beauvais  airport to arrive mid-day at Rome Ciampino airport. There are several shuttle services  available at the airport to take you to the main city center – drop point Roma Termini  main railway station. They are all the same - take the one which is departing  earliest. I had booked a Hotel very close to Roma Termini. It was a simple  budget category hotel – no frills, low cost, clean, and functional. There were  a lot of shops and restaurants nearby. We enjoyed Italian veggie pizzas and  pastas on all three days. Get information from tourist info centre at the main  station. They are quite helpful. They speak English. I had made my own little sight-seeing  wish-list before-hand. With this list as a starting point, and their generous help,  we were able to chalk out a detailed plan for the rest of trip. The Metro (underground  train) service is very good. Make sure you take city tourist maps, maps & info  about Metro, Bus, etc. from the counter. Travelling within Rome Rome 
Day 2 (Full useful day)
The Glories of Ancient Rome 
We reached here by Bus around 12:00 – you should reach as early  as possible.
Colosseum  - Ancient Rome 's huge amphitheater was built in  between 70 and 82 AD in the heart of Rome 
Roman  Forum : a huge complex of ruined temples, basilicas, and arches, was the  ceremonial, legal, social, and business center of ancient Rome Palatine   is included in the Colosseum/Roman Forum ticket. From the Palatine ,  you can also see the Circus  Maximus, famed for its chariot races.
We took some wrong paths and ended in dead-end – try to avoid  such things as you have to conserve energy and time. When in doubt anywhere - Ask  ask and ask till you are sure. Make sure you keep strict eye on your watch. The  sign-boards here are not always correct. So keep observing the tourist movement  around – if you find a guided tour group, the guide may help you with  directions. This place is so huge – you easily spend the full day wandering  around. Look for the panoramic view point. From there try to locate and identify  the structures and buildings in the map.
We then came out of the Forum and walked till the Piazza Venezia. It is a large traffic circle  in front of the magnificent  Monument to Vittorio Emanuele II.  After clicking several pics, we moved on to The Pantheon. We asked people how  to reach there – everyone knows English here. The Pantheon,  is the best preserved building of ancient Rome Rome Rome  at sunset, climb the  stairs and walk left to the Pincio  Gardens Pincio  Gardens 
Day 3 (Depart Rome 
Vatican Museums - At the  Vatican Museums you choose from 4 different itineraries all ending with the  Sistine Chapel. Because of the vastness of the museum it's wise to take a guided  tour. Do some homework research and shortlist the main exhibits you don't  want to miss there. These exhibits could become the basis of selecting the visit  routes. Audio Guides and guided tours were not our thing – so we skipped them. Believe  me – it is huge. I strongly suggest you do a booking online in  advance. The queue for the entrance can be unimaginably long. We arrived around  11:00 and were shocked to see a long serpentine queue already waiting. In our  estimate it would have taken at least 2 hours to reach the ticket counter. We definitely  did not want to waste precious hours waiting in the queue. We had to think of  an alternative – we swapped the Day 3 and Day 2 itineraries and went on to explore  "The Glories of Ancient Rome". 
St. Peter's Basilica 
Saint Peter's Basilica, built on the site of a church  covering Peter's tomb, is one of the largest churches in the world. Entrance to  the church is free but visitors must be properly dressed, with no bare knees or  shoulders. Saint Peter's Basilica is open daily, 7AM - 7PM (until 6PM October -  March). Masses, in Italian, are held all day on Sundays.
1.       Vatican Dome  – It costs 7€ / person. You can go up the dome of Vatican 
2.       Tomb of  Previous Popes – Here you can find tombs of previous popes not all though.
3.       Basilica –  This is the cathedral. Here you can find St.    Peters 
Sistine Chapel: The  Sistine Chapel was built from 1473-1481 as both the pope's private chapel and  the venue for the election of the new pope by the cardinals.
Castel Sant Angelo: ( we did not  visit this) Castel Sant Angelo, on the Tiber  River Vatican 
 
